Kaleb has a weakness for exotic animals, which he guards in his apartment in a Parisian apartment block. His latest achievement is a rare spider of unknown origin: particularly aggressive, extremely poisonous and highly invasive. Soon there are the first fatalities and the whole building is shrouded in cobwebs. Fleeing from the biting army of eight-legged creatures, Kaleb and his friends have to fight their way to freedom floor by floor...