Robert Langdon, a Harvard symbologist, accompanies his girlfriend Katherine Solomon to Prague. Katherine is preparing the publication of a book that reveals groundbreaking discoveries about the true nature of human consciousness. But a brutal murder plunges the trip into unforeseen chaos, and Katherine suddenly disappears, along with her manuscript. Langdon now finds himself facing a powerful organization and is pursued by a sinister assailant who seems to have stepped out of Prague's oldest mythology and has only one goal: merciless revenge.