Arizona, 1849: In a land ravaged by death, violence, and religious fanaticism, rumors spread about a girl possessed by the devil. Every living being she touches dies mysteriously. Seeking a cure, the widowed and ether-addicted Dr. Bender agrees to accompany the child and her mother on their perilous journey across the fire-ravaged land. While Bender initially believes in a rational explanation for the girl's enigmatic illness, his conviction gradually begins to waver...